UPDATE!
Be sure to read MD’s comments (below) before using FactMed to assess the side effects of whatever med you’re curious about. Try to find the information published by your medication’s maker — if you have a generic Rx, you usually can find a source on the net that will tell you the brand name if you enter the generic name.
Every now and again, you need a source for side effects of medications that is NOT a woo-woo naturopathic site like LiveStrong or any of the myriad sites of the various quacks who try to convince you that their snake oil is better than researched, tested prescription drugs. WebMD always comes up relatively high in a list of search results, and sometimes the Mayo Clinic will have a page describing the uses and potential side effects of various nostrums. The Mayo is reliable enough as a reference, but WebMD has occasionally been questioned.
I recently came across a site called FactMed. It’s a searchable database based on “more than 18 million FDA adverse drug reports for 20,000 different pharmaceutical products.” If you explore around in there, you find a search engine that will let you enter a drug and a specific ailment that you suspect might be a side effect.
Results show the proportion of patients reporting side effects who reported THAT side effect. So, if 100 patients reported that they’d had some side effect of a given med and 5 of them said the med gave them a roaring headache, you would be able to see that 5% of people who had some effect had reported “roaring headache” as the problem. It also shows you the proportion of ALL medicated patients reporting that as a side effect, and it provides a graph showing the proportion of physicians who reported that they highly suspected the med was a cause, that they thought it was a “likely culprit,” or that they thought a connection was highly unlikely.
This is extravagantly useful information. Even though, yes, correlation is not causation, FactMed at least provides some quantitative data to help you assess whether some symptom might be attributed to a drug or combination of drugs you’re taking, and it gives you some credible ammunition when you need to discuss any such issue with your doctor.
The cardiologist and I have been trying to figure out what caused the episode of presyncope (near-fainting) that occurred while I was flying westward across a major surface artery at 50 mph a few weeks ago. Since it was accompanied by a spate of heart palpitations, we of course have suspected a cardiac issue. But so far he has been unable to find any indication of a heart problem. Even my blood pressure, a subject docs love to harp upon, is well into the normal range.
Consequently, he has lashed me up in a Holter monitor — a device that listens to your innards 24/7 — and asked me to wear it for a full freaking MONTH!
This is making me unhappy, partly because it’s very hard to find any clothing that you can wear around such a thing without looking like Frankenstein’s monster, but more to the point because the cables they tape to your chest irritate the perennially sensitive mastectomy scars. These cannot be avoided, because they stretch from armpit to armpit. The discomfort is annoying during the day and makes sleeping almost impossible.
So I intend to get out of it, but to do so wish to explain a) why I’m not doing this and b) why I think it’s reasonable to believe the pseudoephedrine (Sudafed) pill I dropped that morning on top of a full pot of strong black coffee brought all this on.
And lo! Here it is, right in the FactMed database:
This stuff doesn’t just cause presyncope: it actually causes people to lose consciousness:
Proportion of pseud. patients reporting loss of consciousness as side effect: 4.6% [Holy sh!t! That’s almost 5%!]
Proportion of all medicated patients reporting loss of consciousness as side effect: .32%
Number of patients reporting side effects from pseudoephedrine: 999
As for heart palpitations…interesting:
Proportion of pseud. patients reporting palpitations as side effect: 3.0%
Proportion of all medicated patients reporting palpitations as side effect: .33%
If a medication has a weird, rare side effect, I invariably experience it. For godsake, if 5% of patients experience syncope after taking this drug, I am extremely lucky I didn’t actually pass out at the wheel and cause a wreck.
Three percent for the palpitations makes it a bit of a longer shot…but again, given my sensitivities to all drugs, prescription or over-the-counter, it strikes me as not all that unlikely that whatever already causes the occasional spates of palpitation could be kicked up by a drug that wires me to the teeth under the best of circumstances and that may cause me to faint.
The sample of about a thousand people isn’t huge, but it’s respectable.
So here’s what, in the self-diagnosis department: I feel enough confidence that whatever brought this on was not a true cardiac issue that I’m going to throw over the electronic traces and return the Holter monitor. I don’t think it’s worth irritating the scars, which are already uncomfortable enough, thank you, by having tubes rubbing on them all day & all night for a full month and by applying allergy-inducing stickum to the skin near them.
It may annoy the doc, but at least I’ll have a little evidence, based FDA reports, to make my case.